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  4. 2022

CNCR researcher receives grant from the EU joint program

Van der Kant and the VU Medical Center receive funding for unravelling the associative link between exercise and lipid metabolism in prevention against Alzheimer.

Optimizing study designs for iPSC-based disease modelling

In a study published in Molecular Psychiatry, Jessie Brunner, Hanna Lammertse and Annemiek van Berkel (FGA) teamed up with Sophie van der Sluis (CTG) and the proteomics facility (MCN) to optimize statistical power for iPSC-based study designs.

The Axon Initial Segment Biology team is live!

Amelie Freal, head of the team, joined CNCR earlier this year and is developing an independent research program on axon initial segment biology at FGA.

PreSSAD awarded, will study early presynaptic AD biomarkers

The PreSSAD consortium of 6 EU partners incl. CNCR (Matthijs Verhage, FGA) was awarded (JPND/Memorabel, pre-diagnosis disturbances in neurodevelopmental disorders) and will start Nov 1st with IPSC-based models of presynaptic degeneration

Three CNCR TenureTrackers rewarded permanent employment contract

The performance of CNCR researchers Rachel Brouwer, Loek van der Kallen and Mahesh Karnani has been evaluated positively and we are happy to announce that they are rewarded a permanent employment contract.

Three CNCR researchers each awarded a VIDI grant

Rik van der Kant, Natalia Goriounova and Priyanka Rao-Ruiz, researchers at the Center for Neurogenomics & Cognitive Research at the Vrije Universiteit Amsterdam, have been awarded by the Dutch Research Council (NWO) with a Vidi grant worth 800,000 euros.

Novel insights into neuronal resilience to proteostatic stress

A new study by Kim Wolzak and colleagues from the team of Wiep Scheper reveals how neurons shift their translational control to ensure proteostatic resilience during ER stress. The study was published in The EMBO Journal.

Million dollar bike ride: teams raise more than 20.000 euro

On Saturday 11th of June we successfully biked the Dutch-Belgian million dollar bike ride, a fundraising event to raise money for research towards STXBP1-Encephalopathy!

Belgian & Dutch STXBP1 labs bike to raise money for research

We bike together to raise money for research towards new treatments for the rare disorder STXBP1 Encephalopathy!

Biggest study so far implicates synaptic genes in schizophrenia

An international consortium analysed DNA from more than 300,000 people with and without the disorder. The SYNGO consortium, coordinated by CNCR, performed the analyses of synaptic genes. The study is published in Nature on April 11th

SFARI director’s award for SYNGO

Guus Smit and Matthijs Verhage obtained funding to coordinate expert annotation of the synaptic protein interactome, with the goal to curate protein-protein interactions implicated in autism.

New study on neuropathies upon loss of TDP43-regulated RNA Stmn2

Irune Guerra San Juan (FGA) & team show neuropathies may develop in ALS patients when a poison exon in Stmn2 mRNA is not excised due to TDP43 dysfunction. The study is a collaboration with Harvard University published in Neuron on March 15th

SYNGO2 starts with new 2 year support from The Broad Institute

The SYNGO consortium, coordinated by CNCR, enters a new phase to annotate/curate protein-protein interactions in the synapse with two more years of funding for the Amsterdam office.

CNCR STXBP1 team wins social media challenge

This February, the Orphan Disease Center challenged researchers worldwide to share social media posts about the rare disease they are working on . The three most creative and popular posts were selected as winners on Feb.28th, Rare Disease Day 2022. The CNCR STXBP1 team is one of the winners
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